Clean the boom sprayer according to the label of the material you sprayed last, and pull the nozzles and strainers before you flush the plumbing with clean water. A clean-water rinse on its own will not carry a different material safely into the next tank.
The reason is mechanical more than chemical. Residue collects in the small parts the liquid passes through last, meaning the strainer screens ahead of each tip, the tips themselves, and the fittings at the end of the boom. A flush pushed through a fully assembled boom moves loosened material along those same passages on its way out. Take them out of the circuit first and the water has an exit that does not run back through the metering orifice.
Before the First Rinse, Read the Last Label
The label of the material you just finished spraying is the document that sets the cleaning method, and it is specific to that material rather than to sprayers in general. Cleaning directions follow the product used last, and the water doing the work is clean water. Formulations leave different films behind, so a sequence built for one product is not automatically the right sequence for the next one, and blending two labels into one procedure produces a method neither of them describes.
Keep the label page with the spray record for that load. On most farms the person who cleans the rig is not always the person who filled it, and the label is the only place the directions exist in a form the next operator can follow without guessing. In the first week a new product is on the farm, that page is also what keeps a crew from mixing a stronger batch to be safe, which is one route to exceeding the labeled rate.
After the Last Tank, Pull Nozzles and Strainers
The first mechanical action after the last tank is removal, not rinsing. Take off the nozzles and the filter and strainer screens, clean them, then flush the sprayer's plumbing system with clean water before a different spray material goes in. The strainer is the screen that sits ahead of the tip and catches grit before it reaches the orifice; the nozzle tip is the part that meters flow and sets the pattern.
Leaving those parts in place also hides what you most need to look at. A torn screen mesh or a swollen seal is visible in your hand and invisible inside an assembled fitting, and the end-of-day look at the rig only covers what you can actually see. If the sprayer is used and new to you, ask what went through it last and whether that label came with the machine; without the label, the first changeover has no directions to follow.
Clean Tips With a Soft Brush, Not Metal
Tips are the one place in the system where an impatient shortcut risks permanent damage. Do not use any metal object when cleaning sprayer tips; use a soft brush and a can of compressed air. A wire, a knife blade or a tip cleaner can open a clogged orifice, and it can also scratch or ream the opening that meters the spray, after which the tip may no longer deliver what it delivered before anyone touched it.
Keep the soft brush and the air can in the cleaning kit, so the right tool is the one within reach when a tip plugs at the end of a long day. A tip cleaned with whatever is handy is a tip that gets replaced early for a reason nobody wrote down. A spare set of tips on the shelf is the alternative to spraying a season through an orifice someone opened with a wire.
Before the Next Material, Flush the Plumbing
Tips off. Then water. With the nozzles and strainers out of the circuit, the flush has somewhere to send what it loosens: out through open ports rather than into the screens and fittings that are about to go back on the boom. The material going in next is what the flush is protecting, which is why the flush runs before that material is mixed, not after.
How much water goes through, and whether anything beyond clean water belongs in it, come from the label of the material last used and from nowhere else. A cleaning charge mixed from memory is a solution with no directions behind it. Where the rinse water goes is a question for the label and for your state pesticide authority, and it is worth answering before the tank is full rather than after.
By Day's End, Check for Rust and Leaks
Clean, then look. Thoroughly clean the spray rig and check for signs of rust, leaks or other problems while the surfaces are bare; a weep at a fitting or a rust bloom at a clamp shows up on a washed boom and disappears under dried residue.
A leak caught at this point is a fitting you can deal with before the next load goes in. The same leak during the next application turns into a strip in the field, and by then you are reading a crop symptom to diagnose a plumbing problem. Write the check down beside the cleaning entry, because a weep noted last time and still there now is a fitting to deal with rather than a note to repeat.
Before the Next Spray Day, Walk the Changeover
Walk the changeover once before the next spray day, in order, out loud if that is what it takes to make the order stick. The label for the material just used comes first, because it decides everything downstream and it is the only document that says whether clean water alone is the whole job. Then the nozzles and strainers come off and get cleaned, before anything runs through the boom. Tips get the soft brush and the compressed air and nothing metal. The plumbing gets water with the tips and screens outside the circuit. The rig gets cleaned, checked for rust, leaks or other problems, and reassembled.
Order is what produces the result, not the individual steps on their own. A label-matched method attacks the residue that is actually in the tank. Pulling the nozzles and screens first turns the flush into a one-way trip. Soft tools leave the metering orifice the size it was. Flushing with those parts outside the circuit sends loosened material away from the fittings. And a rig that is clean before it is inspected shows its rust and its leaks while there is still time to act on them.
These are cleaning principles from university extension material, applied to a boom sprayer. They do not replace the label for whatever product is in your tank, and nothing here is a measured performance claim.
Imagine the season running that way. In the first week the changeover usually runs slower than the spraying on either side of it, which makes it the week to write the sequence down and hang the sheet on the sprayer. A month in, the sequence runs without the sheet. Three months into the season, the record of which label was followed, when the tips and screens came off, and what the end-of-day check found is what tells you whether the routine held or quietly collapsed into a rinse.
What it costs is handling. Pulling and cleaning tips and screens between every material change adds work to a day that is already long, and label-directed cleaning can take longer than the rinse the crew is used to. What that buys is a boom that is not carrying the last product into the next tank, tips whose openings have not been reamed out, and a rust or leak check done while the rig is clean. Rinse-and-go gives up all three to save the handling.

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